UHPLC Column, RP C4 Butyl, 1.8um, 100A. 4.6mm ID x 50mm Length. Cogent Brand. 1 EA.
Additional Information:
Cogent RP C4 Butyl is a reversed-phase HPLC and UHPLC stationary phase designed for the separation of hydrophobic to moderately hydrophobic compounds. Manufactured using a traditional butyl (C4) bonded phase on ultra-high purity silica and fully double end capped, it provides reproducible retention, excellent peak shape, and reduced secondary interactions. The shorter alkyl chain offers less retention than C8 or C18 phases, making it well suited for fast analyses, biomolecules, peptides, proteins, and method development where excessive retention is undesirable.
68104-05P is a UHPLC column packed with 1.8 µm RP C4 Butyl particles featuring a 100 Å pore size in a 4.6 mm ID x 50 mm format. The short 50 mm length is optimized for high-speed separations, while the 1.8 µm particle technology provides exceptional efficiency, increased peak capacity, and superior chromatographic performance compared to larger particle columns. This column is specifically designed for high-pressure UHPLC applications and delivers the greatest performance benefits when used on a UHPLC system capable of operating at the elevated pressures generated by sub-2 µm particles. Typical operating flow rates are approximately 1.0–2.0 mL/min depending on mobile phase viscosity, instrument pressure limitations, and application requirements.
Ideal for very hydrophobic and neutral compounds, this column offers rapid analysis times, reduced solvent consumption, increased laboratory throughput, and excellent performance for method development. While it may be used on compatible HPLC systems, the column is engineered and intended primarily for UHPLC operation where its full efficiency and speed advantages can be realized.
Key Benefits
RP C4 Butyl stationary phase
Fully double end capped
Traditional butyl bonded phase
Ultra-high purity silica support
Engineered for UHPLC applications
1.8 µm particle technology
Exceptional column efficiency
Increased peak capacity
Fast analysis times
Reduced solvent consumption
Typical Applications
UHPLC analysis
High-speed separations
Method development
Peptide analysis
Protein analysis
Hydrophobic compound analysis
Neutral compound analysis
Pharmaceutical analysis
Bioanalytical applications
High-throughput laboratories
Specifications
Product Type: UHPLC Column
Stationary Phase: RP C4 Butyl
Chromatography Mode: Reversed Phase
Bonded Phase: Butyl (C4)
Endcapping: Fully Double End Capped
Particle Size: 1.8 µm
Pore Size: 100 Å
Column Dimensions: 4.6 mm ID x 50 mm
Length: 50 mm
Typical Flow Rate: 1.0–2.0 mL/min
Brand: Cogent
Important Notes
Specifically designed for UHPLC operation and high-pressure reversed-phase separations
May be used on compatible HPLC systems, but maximum performance benefits are achieved on UHPLC instruments
Sub-2 µm particles generate significantly higher backpressure than conventional HPLC columns
A UHPLC system capable of operating at the required pressures is recommended
Samples should be filtered through a 0.2 µm syringe filter prior to injection
Short column length provides rapid analysis and increased sample throughput
Lower retention than comparable C8 or C18 stationary phases